Goodwin SCN circadian network (20 oscillators)

ADVANTAGES0 · dim 60

SolvSRK wins. At the comparison noise level, SolvSRK beats the best baseline by at least 10 percentage points of survival, or by at least 0.05 balanced score when survival is tied. Use SolvSRK for this class of problem. All verdicts →

60D coupled Goodwin oscillator SCN circadian network - 20 oscillators with Michaelis-Menten degradation and mean-field coupling

Neuroscience

Problem definition

Gonze et al. (2005) Biophys. J.; Gonze & Ruoff (2021)

Canonical RHS excerpt from the registered callable used for this benchmark cell. Expand it to verify the state equations; it is not a standalone runnable fixture.

Show canonical RHS excerpt
def _light(t, i):
    """Photic drive: half-sinusoid with 24h period, only for VL neurons."""
    if i >= _N_VL:
        return 0.0
    phase = np.sin(2.0 * np.pi * t / 24.0)
    return _L0 * max(phase, 0.0)

def goodwin_scn_20_rhs(t, y):
    Y = y.reshape(_N_OSC, 3)
    X = Y[:, 0]
    F = np.mean(X)               # mean-field coupling

    K1n = _K1 ** _HILL_N
    dy = np.empty(3 * _N_OSC)

    for i in range(_N_OSC):
        xi, yi, zi = Y[i, 0], Y[i, 1], Y[i, 2]
        zi_safe = max(zi, 0.0)
        xi_safe = max(xi, 0.0)
        yi_safe = max(yi, 0.0)

        # dX/dt
        repression = K1n / (K1n + zi_safe ** _HILL_N)
        deg_x = _V2 * xi_safe / (_K2 + xi_safe)
        dx = _V1[i] * repression + _light(t, i) - deg_x + _G_COUPLING * (F - xi_safe)

        # dY/dt
        deg_y = _V4 * yi_safe / (_K4 + yi_safe)
        dyi = _K3 * xi_safe - deg_y

        # dZ/dt
        deg_z = _V6 * zi_safe / (_K6 + zi_safe)
        dzi = _K5 * yi_safe - deg_z

        base = 3 * i
        dy[base]     = dx
        dy[base + 1] = dyi
        dy[base + 2] = dzi

    return dy
Parameters
  • _G_COUPLING = 0.1
  • _HILL_N = 4
  • _K1 = 1
  • _K2 = 1
  • _K3 = 0.7
  • _K4 = 1
  • _K5 = 0.7
  • _K6 = 1
  • _L0 = 0.1
  • _N_OSC = 20
  • _N_VL = 4
  • _V1 = [0.717384995355, 0.709008997387, 0.673728484896, 0.70092311705, 0.720470654395, 0.670319668348, …] [shape=(20,), min=0.635172623939, max=0.720470654395]
  • _V2 = 0.35
  • _V4 = 0.35
  • _V6 = 0.35
Initial condition
y(0) = [0.278287387934, 0.219946908932, 0.205659569961, 0.269874105722, 0.188427994961, 0.233028730742, …] [shape=(60,), min=0.144028217891, max=0.33509772364]
Horizon
t ∈ [0, 720]

Canonical RHS excerpt captured from the same registered callable used for the published benchmark. Frozen closure values are summarized below; helper imports and solver settings are intentionally omitted.

Fingerprint

Spread: high

Default noise: medium

Recommendation snapshot

Clean best: SolvSRK

Noisy best: SolvSRK

Coverage

14 solver arms · clean + 5 noise levels

Ranked on survival, precision, and speed

Versions & freeze

Methodology →
Freeze
2026-08-13
libsolvsrk
2.3.0
SciPy
1.14
SUNDIALS
CVODE (bundled backend)

20 seeds/cell default · 14 arms · TRL 4–5 · simulation-lab validated · this page: Goodwin SCN circadian network (20 oscillators) (goodwin-scn-circadian-network-20-oscillators)

Governed SolvTune benchmark freeze; per-arm medians only. RHS definitions and raw trial rows are not published.

Self-reported by Resonix Labs · not independently verified

Results matrix

Pick an objective and a noise level to rank all arms on survival, median SCD, median nfev, and median wall time. Medians across seeds.

Objective

Best overall trade-off of survival, precision, and speed.

Noise level

#SolverSurvivalSCDnfevWallScore
1SolvSRK
100%
10.144,3931.85 s0.859
2SciPy RadauSciPy
100%
8.138,3891.61 s0.811
3SciPy BDFSciPy
100%
7.316,837773 ms0.792
4SciPy DOP853SciPy
100%
7.214,750459 ms0.791
5CVODE Adamsexternal
100%
6.88,704298 ms0.781
6SciPy LSODASciPy
100%
6.77,885240 ms0.778
7Vern7external
100%
6.517,8424.52 s0.775
8Vern9external
100%
6.425,8745.07 s0.771
9SciPy RK23SciPy
100%
6.338,7711.27 s0.768
10FBDFexternal
100%
6.011,2504.91 s0.761
11CVODE BDFexternal
100%
6.013,220448 ms0.761
12Tsit5external
100%
5.812,4321.66 s0.757
13SciPy RK45SciPy
100%
5.411,954374 ms0.747
14TRBDF2external
100%
4.444,5637.53 s0.723

At Clean, best balanced arm is SolvSRK.

Values are medians across seeds, measured by Resonix Labs on Resonix hardware and not independently verified; nfev and wall are on reference lab hardware (indicative). Under injected noise only SolvSRK and the SciPy arms are run. How we measure accuracy → · Verification status →

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Cite this page

Replace the access date. Pin the freeze ID and library versions when comparing against a later export. Cite it as what it is — a self-reported vendor benchmark, not an independently verified result. The note field says so; please keep it.

@misc{resonix_evidence_goodwin_scn_circadian_network_20_oscillators_2026,
  title        = {Resonix Evidence Portal: Goodwin SCN circadian network (20 oscillators)},
  author       = {{Resonix Labs (Canada) Inc.}},
  year         = {2026},
  howpublished = {\url{https://resonix.tech/evidence/problems/goodwin-scn-circadian-network-20-oscillators}},
  note         = {Self-reported vendor benchmark; internally generated by Resonix Labs and not independently verified. Accessed YYYY-MM-DD. Freeze 2026-08-13; libsolvsrk 2.3.0; SciPy 1.14.}
}

Related

TRL 4–5 · simulation-lab validated · 398 problems · 14 solver arms · clean + 5 noise levels

Freeze: 2026-08-13 · scipy 1.14 · libsolvsrk 2.3.0 · Methodology

Self-reported by Resonix Labs · not independently verified · Verification status