Wendling extended (fast/slow inhibition)

PARITYS1 · dim 10

No clear winner. The survival gap is under 10 percentage points and the balanced-score gap is under 0.05, so neither SolvSRK nor the best baseline clears the win threshold. Either works — choose on cost, licensing, or integration effort. All verdicts →

10D Wendling model with four populations: pyramidal, excitatory, slow inhibitory (b=50/s), fast inhibitory (g=500/s). Three timescales with g/b = 10:1 stiffness ratio.

Neuroscience

Problem definition

Wendling et al. (2002); Hebbink et al. (2020), CNSNS

Canonical RHS excerpt from the registered callable used for this benchmark cell. Expand it to verify the state equations; it is not a standalone runnable fixture.

Show canonical RHS excerpt
def _stable_expit(x):
    """Numerically stable sigmoid 1/(1+exp(-x)), scalar or array."""
    x = np.asarray(x, dtype=float)
    return np.where(
        x >= 0,
        1.0 / (1.0 + np.exp(-x)),
        np.exp(x) / (1.0 + np.exp(x)),
    )

def _jr_sigmoid(v, v_max=5.0, r=0.56, v0=6.0):
    """Jansen-Rit population sigmoid: S(v) = v_max / (1 + exp(r*(v0 - v)))."""
    return v_max * _stable_expit(r * (v - v0))

def rhs(t: float, y: np.ndarray) -> np.ndarray:
    y0v, y1v, y2v, y3v, y4v = y[0], y[1], y[2], y[3], y[4]
    y5v, y6v, y7v, y8v, y9v = y[5], y[6], y[7], y[8], y[9]

    S_pyr = _jr_sigmoid(y1v - y2v - y3v)
    S_exc = _jr_sigmoid(C1 * y0v)
    S_slow = _jr_sigmoid(C3 * y0v)
    S_fast = _jr_sigmoid(C5 * y0v - C6 * y4v)
    S_self = _jr_sigmoid(C3 * y0v)

    return np.array([
        y5v,                                                # ẏ₀
        y6v,                                                # ẏ₁
        y7v,                                                # ẏ₂
        y8v,                                                # ẏ₃
        y9v,                                                # ẏ₄
        A * a * S_pyr - 2.0 * a * y5v - a2 * y0v,          # ẏ₅
        A * a * (p + C2 * S_exc) - 2.0 * a * y6v - a2 * y1v,  # ẏ₆
        B * b * C4 * S_slow - 2.0 * b * y7v - b2 * y2v,    # ẏ₇
        G * g * C7 * S_fast - 2.0 * g * y8v - g2 * y3v,    # ẏ₈
        B * b * S_self - 2.0 * b * y9v - b2 * y4v,         # ẏ₉
    ])
Parameters
  • A = 3.25
  • B = 22
  • C1 = 135
  • C2 = 108
  • C3 = 33.75
  • C4 = 33.75
  • C5 = 40.5
  • C6 = 13.5
  • C7 = 108
  • G = 10
  • a = 100
  • a2 = 10000
  • b = 50
  • b2 = 2500
  • g = 500
  • g2 = 250000
  • p = 220
  • v_max = 5
  • r = 0.56
  • v0 = 6
Initial condition
y(0) = [1e-06, 1e-06, 1e-06, 1e-06, 1e-06, 1e-06, 1e-06, 1e-06, 1e-06, 1e-06]
Horizon
t ∈ [0, 2]

Canonical RHS excerpt captured from the same registered callable used for the published benchmark. Frozen closure values are summarized below; helper imports and solver settings are intentionally omitted.

Fingerprint

Spread: high

Default noise: medium

Recommendation snapshot

Clean best: Vern9

Noisy best: SciPy RK45

Coverage

14 solver arms · clean + 5 noise levels

Ranked on survival, precision, and speed

Versions & freeze

Methodology →
Freeze
2026-08-13
libsolvsrk
2.3.0
SciPy
1.14
SUNDIALS
CVODE (bundled backend)

20 seeds/cell default · 14 arms · TRL 4–5 · simulation-lab validated · this page: Wendling extended (fast/slow inhibition) (wendling-extended-fast-slow-inhibition)

Governed SolvTune benchmark freeze; per-arm medians only. RHS definitions and raw trial rows are not published.

Self-reported by Resonix Labs · not independently verified

Results matrix

Pick an objective and a noise level to rank all arms on survival, median SCD, median nfev, and median wall time. Medians across seeds.

Objective

Best overall trade-off of survival, precision, and speed.

Noise level

#SolverSurvivalSCDnfevWallScore
1Vern9external
100%
11.625,8103.40 s0.896
2SciPy DOP853SciPy
100%
11.222,742398 ms0.885
3Vern7external
100%
10.826,0423.42 s0.876
4SciPy RadauSciPy
100%
9.449,9861.25 s0.843
5Tsit5external
100%
9.025,4462.14 s0.834
6SolvSRK
100%
9.023,399606 ms0.833
7SciPy RK45SciPy
100%
8.730,440552 ms0.826
8CVODE Adamsexternal
100%
6.43,53672 ms0.771
9FBDFexternal
100%
6.39,6613.70 s0.769
10SciPy LSODASciPy
100%
5.88,157136 ms0.757
11SciPy BDFSciPy
100%
5.811,499369 ms0.756
12SciPy RK23SciPy
100%
5.666,7071.27 s0.753
13CVODE BDFexternal
100%
5.65,104102 ms0.753
14TRBDF2external
100%
1.226,2084.24 s0.649

At Clean, best balanced arm is Vern9 · SolvSRK survival 100%, SCD 9.0.

Values are medians across seeds, measured by Resonix Labs on Resonix hardware and not independently verified; nfev and wall are on reference lab hardware (indicative). Under injected noise only SolvSRK and the SciPy arms are run. How we measure accuracy → · Verification status →

SolvScout · free

Profile your problem for free

This page shows one published benchmark cell. SolvScout fingerprints your ODE, compares it to the full corpus, and recommends a solver with the same survival / precision / speed ranking you see here — including when a SciPy arm wins.

SolvSRK · 30-day trial

Run the winner on your machine

SolvSRK is the stiffness-adaptive integrator behind the SolvSRK column in these tables. Create an account, activate a machine, and take a 30-day trial — same binary you'd ship after purchase.

Cite this page

Replace the access date. Pin the freeze ID and library versions when comparing against a later export. Cite it as what it is — a self-reported vendor benchmark, not an independently verified result. The note field says so; please keep it.

@misc{resonix_evidence_wendling_extended_fast_slow_inhibition_2026,
  title        = {Resonix Evidence Portal: Wendling extended (fast/slow inhibition)},
  author       = {{Resonix Labs (Canada) Inc.}},
  year         = {2026},
  howpublished = {\url{https://resonix.tech/evidence/problems/wendling-extended-fast-slow-inhibition}},
  note         = {Self-reported vendor benchmark; internally generated by Resonix Labs and not independently verified. Accessed YYYY-MM-DD. Freeze 2026-08-13; libsolvsrk 2.3.0; SciPy 1.14.}
}

Related

TRL 4–5 · simulation-lab validated · 398 problems · 14 solver arms · clean + 5 noise levels

Freeze: 2026-08-13 · scipy 1.14 · libsolvsrk 2.3.0 · Methodology

Self-reported by Resonix Labs · not independently verified · Verification status